Вплив пептидоглiкану Staphylococcus aureus Wood 46 на киснезалежний метаболiзм макрофагiв i нейтрофiлiв

Abstract

The effect of peptidoglycan from Staphylococcus aureus Wood 46 on the cytotoxic activity of macrophages and neutrophils is investigated. It is shown that bacterial peptidoglycan increases spontaneous and stimulated TPA (respiratory burst) in both populations of phagocytes. More sensible to murein is neutrophil. The action of peptidoglycan from S. aureus Wood 46 on the metabolism of these cells is dose-depended with maximal stimulating effect at the addition of 10 mkg/ml of peptidoglycan in combination with TPA.