Ефект ацетил-L-карнiтину на мiтохондрiальну функцiю та вивiльнення серотонiну при цукровому дiабетi

Abstract

A close relation between the impaired energy metabolism and the serotonin release from isolated synaptic terminals is established. These data suggest a substantial role of mitochondria in the derangement of the synaptic function associated with diabetes. Positive neuromodulatory role of acetyl-L-carnitine on the serotoninergic system is found. It is most likely to be mediated by it’s normalizing effect on the energy metabolism.