Навантажені антибіотиком біоматеріали медичного призначення на основі біогенного гідроксиапатиту з феромагнітними добавками

Abstract

The possibility of using the composite materials of biological nature, in particular biogenic hydroxyapatite (BHA) with magnetic additives and without it, as broad spectrum antibiotic carrier for orthopedics and traumatology was shown. It was found that the unalloyed sample being in the model medium has a lesser velocity of bioresorption (0.70 % mass./ day) especially in a first 2 days than alloyed sample (1.11 % mass./ day). At the same time both materials have an identical tendency into maximal saturation by antibiotic for 2 hours, however the composite system BHA / Fe₃O₄ has a twice less value of adsorption activity compared with BHA.